Air or Gas Embolism — As the primary treatment for embolism, HBOT decreases bubble size, reduces mortality/morbidity and the development of permanent neurological damage. At the present time there is no alternative therapy.

Decompression Sickness (The Bends) — As the primary treatment, HBOT rapidly clears inert gas bubbles and provides oxygenation to ischemic and hypoxic tissues. No alternative therapy is currently available.

Carbon Monoxide Poisoning and Smoke Inhalation — Considered mandatory for severe CO poisoning, HBOT mitigates tissue poisoning and significantly reduces permanent neurologic damage. HBOT also has a direct effect in reducing the toxicity of cyanide.

Gas Gangrene — When used in conjunction with surgery and antibiotics, HBOT significantly reduces morbidity and mortality. HBOT inhibits the production of lethal alpha-toxin produced by Clostridium perfringens.

Crush Injury and Traumatic Wounds — HBOT increases tissue oxygen levels by increasing oxygen delivery, and significantly reduces tissue edema through its vasoconstrictive effect.

Problem Wounds — HBOT causes a 10-15 fold increase in plasma oxygen and a 2-3 fold increase in oxygen diffusion distance. This restores a favorable cellular environment, stimulates fibroblasts to form adequate collagen, increases neovascularization by 20% and enhances leukocyte activity. HBOT has been proven effective in promoting faster, more thorough healing of problem wounds.

Compromised Skin Grafts, Flaps and Replants — Following ischemia or  vascular repair where there has been

Necrotizing Soft Tissue Infections — Used as adjunct therapy to debridement and systemic antibiotics, HBOT reduces anaerobic bacterial growth and increases leukocyte activity. Studies indicate it can decrease mortality by two-thirds.

Refractory Osteomyelitis — Effective in bone infections and in the presence of localized or systemic host compromise, HBOT is used in cases of chronic osteomyelitis as adjunct therapy to antibiotics, debridement, nutritional support and reconstructive surgery.

Radiation Tissue Damage — In conjunction with surgical treatment, HBOT stimulates function capillary growth, fibroblastic proliferation and collagen synthesis in radiated bone and soft tissue. HBOT allows grafting of soft tissue or bone in previously irradiated tissue.

Thermal Burns — As adjunct to standard burn treatment, HBOT helps maintain microvascular integrity, minimizes edema and provides the substrate necessary to maintain viability. With HBOT, mortality, hospital stay and grafting need are markedly reduced.

Exceptional Blood Loss Anemia — When transfusion is refused by the patient, HBOT dissolves enough oxygen in the plasma of severely anemic patients to support basic metabolic needs until RBCs can be restored.

Adjunctive Hyperbaric Oxygen in Intracranial Abcess — Current literature has shown that the mortality rate in Pediatric and ICA patients can be reduced from 17% to 0% using HBOT.